Neural Information Processing Systems http://nips.cc/

Diabetes is a serious worldwide health issue, and successful intervention depends on early detection. However, overlapping risk factors and data asymmetry make prediction difficult. To use extensive health survey data to create a machine learning framework for diabetes classification that is both accurate and comprehensible, to produce results that will aid in clinical decision-making. Using the BRFSS dataset, we assessed a number of supervised learning techniques. SMOTE and Tomek Links were used to correct class imbalance. To improve prediction performance, both individual models and ensemble techniques such as stacking were investigated. The 2015 BRFSS dataset, which includes roughly 253,680 records with 22 numerical features, is used in this study. Strong ROC-AUC performance of approximately 0.96 was attained by the individual models Random Forest, XGBoost, CatBoost, and LightGBM.The stacking ensemble with XGBoost and KNN yielded the best overall results with 94.82\% accuracy, ROC-AUC of 0.989, and PR-AUC of 0.991, indicating a favourable balance between recall and precision. In our study, we proposed and developed a React Native-based application with a Python Flask backend to support early diabetes prediction, providing users with an accessible and efficient health monitoring tool.

Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used ensemble modeling and explainable AI (XAI) techniques to create an interpretable machine learning framework for stroke risk prediction. A thorough evaluation of 10 different machine learning models using 5-fold cross-validation across several datasets was part of our all-inclusive strategy, which also included feature engineering and data pretreatment (using Random Over-Sampling (ROS) to solve class imbalance). Our optimized ensemble model (Random Forest + ExtraTrees + XGBoost) performed exceptionally well, obtaining a strong 99.09% accuracy on the Stroke Prediction Dataset (SPD). We improved the model's transparency and clinical applicability by identifying three important clinical variables using LIME-based interpretability analysis: age, hypertension, and glucose levels. Through early prediction, this study highlights how combining ensemble learning with explainable AI (XAI) can deliver highly accurate and interpretable stroke risk assessment. By enabling data-driven prevention and personalized clinical decisions, our framework has the potential to transform stroke prediction and cardiovascular risk management.

Financial time series forecasting is central to trading, portfolio optimization, and risk management, yet it remains challenging due to noisy, non-stationary, and heterogeneous data. Recent advances in time series foundation models (TSFMs), inspired by large language models, offer a new paradigm for learning generalizable temporal representations from large and diverse datasets. This paper presents the first comprehensive empirical study of TSFMs in global financial markets. Using a large-scale dataset of daily excess returns across diverse markets, we evaluate zero-shot inference, fine-tuning, and pre-training from scratch against strong benchmark models. We find that off-the-shelf pre-trained TSFMs perform poorly in zero-shot and fine-tuning settings, whereas models pre-trained from scratch on financial data achieve substantial forecasting and economic improvements, underscoring the value of domain-specific adaptation. Increasing the dataset size, incorporating synthetic data augmentation, and applying hyperparameter tuning further enhance performance.